Wednesday, January 10th, 2007
Detecting Cell Death with Quantum Dots
By combining a quantum dot with a novel carrier of the magnetic resonance imaging (MRI) agent gadolinium, a team of investigators at the University of Maastricht, in The Netherlands, has developed a nanoparticle that can spot apoptosis, or programmed cell death, using both MRI and fluorescence imaging. Tests in animals showed that this nanoparticle can provide anatomical information using MRI and cellular level information using fluorescence imaging. Imaging programmed cell death in the body could provide an early indication that an antitumor therapy is indeed killing cancer cells.
